Exploiting dendritic cells for active immunotherapy of cancer and chronic infection.
نویسندگان
چکیده
Dendritic cells (DC) are important antigen-presenting cells (APC) that can prime naive T-cells and control lymphocyte-mediated adaptive immune responses with respect to magnitude, memory, and self-tolerance. Understanding the biology of these cells is central to the development of new generation immunotherapies for cancer and chronic infection. This chapter presents a brief overview of DC biology and the preparation and use of DC-based vaccines.
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ورودعنوان ژورنال:
- Methods in molecular medicine
دوره 109 شماره
صفحات -
تاریخ انتشار 2005